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China Journal of Chinese Materia Medica ; (24): 2679-2698, 2023.
Artigo em Chinês | WPRIM | ID: wpr-981372

RESUMO

Cytisine derivatives are a group of alkaloids containing the structural core of cytisine, which are mainly distributed in Fabaceae plants with a wide range of pharmacological activities, such as resisting inflammation, tumors, and viruses, and affecting the central nervous system. At present, a total of 193 natural cytisine and its derivatives have been reported, all of which are derived from L-lysine. In this study, natural cytisine derivatives were classified into eight types, namely cytisine type, sparteine type, albine type, angustifoline type, camoensidine type, cytisine-like type, tsukushinamine type, and lupanacosmine type. This study reviewed the research progress on the structures, plant sources, biosynthesis, and pharmacological activities of alkaloids of various types.


Assuntos
Alcaloides/química , Quinolizinas/farmacologia , Azocinas/química , Fabaceae
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